Glutathione for Skin Lightening. The Science Is In.

The use of glutathione for skin lightening has surged recently, and for very good reason: it works. Glutathione is a powerful antioxidant that has a broad range range of health benefits—not the least of which is skin lightening and hydration.

Here’s what we learn from several recent double-blind, placebo-controlled clinical trials that support the remarkable effects of glutathione on skin health.

1. On Skin Whitening and Lightening

Radiant skin is what everyone wants. To understand skin coloration, we must delve into the melanin index. Melanin, a natural pigment in the skin, determines its shade.

An increase in melanin results in a darker skin tone. Tools like the Mexameter® MX18, are used in these studies to measure the absorption of light to evaluate the skin-whitening efficacy of glutathione.

The focal point was the cheekbone area. By emitting specific wavelengths of light, the Mexameter® MX18 provided data on the melanin content through the amount of reflected light.

Glutathione for Skin Lightening Quote 1: Embrace regular glutathione supplementation to achieve a brighter and more even skin tone.

The results? A significant decrease in the melanin index among subjects using glutathione, indicating a visible whitening or lightening effect. Embrace regular glutathione supplementation to achieve a brighter and more even skin tone.

It should be noted that glutathione for skin lightening was most successful when used topically rather than orally. This is significant and appeared to be consistent in the research, as exemplified in this study:

“Glutathione is one of the agents which is commonly used to lighten skin color in Asia. Studies suggest its potential effect when used topically. The clinical efficacy on skin lightening in oral form is still questionable due to its limited absorption and bioavailability.”

A product like Mimi’s Miracle Glutathione is a great alternative, as it can be taken both orally, and sprayed directly on the skin.

Mimi's Miracle Glutathione® (Spray) -

2. Revitalized Hydration: The Fountain of Youth

Moisturized skin not only feels more supple but also exudes vibrancy while minimizing the appearance of wrinkles. One trial employed the Corneometer®, a device that measures moisture or hydration levels in the facial skin, particularly the cheekbone area. This ingenious tool assesses the moisture content in the stratum corneum, the skin’s outermost layer, using capacitance.

Subjects who incorporated glutathione supplementation experienced a boost in skin moisture levels.

Topically applied glutathione made the skin softer and more hydrated, reducing the likelihood of flakiness, dry patches, and premature signs of aging.

3. Firmness Restored: Bouncing Back with Confidence

As we age, sagging skin becomes a major concern. The firmness and elasticity of our skin determine our youthful appearance. Enter the Triplesense TR-3 sensor scan device, which quantifies skin elasticity.

Those who supplemented with glutathione witnessed a remarkable improvement in skin firmness. This breakthrough is particularly significant for individuals seeking to delay the sagging that accompanies aging, and for those who strive to maintain that radiant and bouncy complexion.

4. Wrinkle Reduction and Smoother Skin: Turning Back the Clock

No skincare regimen would be complete without addressing wrinkles. We all know those pesky “crow’s feet” – those lines at the outer corner of the eyes that tend to be the first wrinkles to appear on the face. The trial evaluated wrinkle reduction and skin smoothening using the SkinSys software alongside a Coccam digital camera.

We all know those pesky “crow’s feet” – those lines at the outer corner of the eyes that tend to be the first wrinkles to appear on the face.

The SkinSys software is a professional tool that offers a comprehensive evaluation of cosmetic products. Through its 3D analysis of skin curvature, it provides tangible evidence of wrinkle reduction. Additionally, by analyzing keratin content with a precise edge-detection algorithm, it sheds light on skin smoothness.

The results were impressive. Subjects who incorporated glutathione supplementation experienced a significant decrease in the appearance of crow’s feet and an overall improvement in skin smoothness. This highlights the potential of glutathione as a natural alternative to invasive anti-aging treatments.

Conclusion: Try Glutathione for Radiant, Youthful, and Healthy Skin

So in conclusion, glutathione for skin lightening is not a myth. Glutathione, well-known for its antioxidant benefits, is now being rediscovered for it’s skin revitalizing properties. From promoting a radiant skin tone to rejuvenating skin texture, it has become a cornerstone of modern skincare routines. The evidence from multiple clinical trials support these claims, demonstrating how this simple molecule can address various skincare concerns.

By incorporating glutathione into your daily life, you can achieve radiant, youthful, and healthy skin. It’s not just about beauty; it’s about holistic wellness and embracing a skincare solution that works from the inside out.


  • Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P. Glutathione and its antiaging and antimelanogenic effects. Clin Cosmet Investig Dermatol. 2017;10:147-153,
  • Dilokthornsakul, W, Dhippayom, T, Dilokthornsakul, P. The clinical effect of glutathione on skin color and other related skin conditions: A systematic review. J Cosmet Dermatol. 2019; 18: 728–737.
  • Handog, E.B., Datuin, M.S.L. and Singzon, I.A. (2016), An open-label, single-arm trial of the safety and efficacy of a novel preparation of glutathione as a skin-lightening agent in Filipino women. Int J Dermatol, 55: 153-157.